YILIMART - CD8 MicroBead Kit, non-human primate

CD8 MicroBead Kit, non-human primate

For research use only

货号：: 130-091-112
描述：: CD8 MicroBead Kit, non-human primate
包装：: for 1×10⁹ total cells

- +

添加到购物车

您浏览过的商品

The CD8 MicroBead Kit was developed for the positive selection or depletion of CD8

⁺

cells from rhesus monkey PBMCs.

Background information

CD8 is expressed on rhesus monkey cytotoxic T cells as well as on a subset of NK cells. The CD8 MicroBead Kit consists of a monoclonal CD8 antibody conjugated to phycoerythrin (CD8-PE) and Anti-PE MicroBeads.

Downstream applications

The kit has been used in the context of developing an

in vitro

viral suppression assay.

It has also been used to investigate T lymphocyte subset responsiveness to vaccine regimens.

Columns

For positive selection: MS, LS, XS, or autoMACS

^®

Columns. For depletion: LD, D, or autoMACS Columns.

Figure 1

Separation of CD8

⁺

cells from rhesus monkey PBMCs using the CD8 MicroBead Kit, a MiniMACS™ Separator, and an MS Column.

PBMCs before separation	CD8 ^- cells

CD8 ⁺ cells

Selected references
1. Loffredo, J. T. et al. (2005)
  
  Tat(28-35)SL8-specific CD8
  ⁺
  T lymphocytes are more effective than Gag(181-189)CM9-specific CD8
  ⁺
  T lymphocytes at suppressing simian immunodeficiency virus replication in a functional
  in vitro
  assay.
  
  J. Virol. 79: 14986-14991
2. Santra, S. et al. (2005) Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. J. Virol. 79: 6516-6522

查看数据文件查看下载