Rat Anti-TCR (T Cell Receptor) γ/δ MicroBeads have been developed for positive selection or depletion of TCRγ/δ
+
T cells from blood, lymphoid tissue, or non-lymphoid tissue, such as gut and liver.
Background information
The epitope recognized by Anti-TCRγ/δ MicroBeads is expressed on more than 90% of TCRγ/δ
+
T cells, which are TCRα/β
-
, CD2
+
, CD3
+
, and CD5
+
. Almost all cells within this population express CD8a, but not CD4. The TCR complex recognized by these MicroBeads is also found on a subpopulation of intestinal intra‑epithelial lymphocytes.
Downstream applications
Magnetically separated TCRγ/δ
+
T cells can be used to investigate their role in immune defense, for example, in comparison to TCRα/β
+
T cells.
Columns
For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, D, or autoMACS Columns.
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