YILIMART - Anti-TCR Vb11-PE, human, REAL368, 100 t

Clone REAL368 is an antibody fragment derived from the full TCR Vβ11 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.

Clone REAL368 recognizes the human Vβ11 T cell receptor (TCR Vβ11). The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vβ11 is expressed on a subset of α/β T cells.

The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

TCR Vβ-11, V beta 11 TCR

Technical specifications

Antigen: TCR Vβ11
Clone: REAL368
Isotype control: REAL Control
Alternative names of antigen: TCR Vβ-11, V beta 11 TCR
Distribution of antigen: T cells
Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Storage: Store protected from light at 2–8 °C. Do not freeze.
Available conjugates: PE

Figure 1

Human peripheral blood mononuclear cells (PBMCs) were stained with REAlease Anti-TCR Vβ11-PE (B) or with the corresponding REAL Control (A). REAlease Anti-TCR Vβ11-PE was released using the REAlease Release Reagent (C). To show epitope accessibility after REAlease Complex release, the cells were washed with the REAlease Stop Reagent and restained with REAlease Anti-TCR Vβ11-PE (D). Cells were labeled with CD3 antibodies in addition and analyzed by flow cytometry using the MACSQuant

^®

Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide (PI) fluorescence.

A:	B:

C:	D:

Anti-TCR Vb11-PE, human, REAL368, 100 t

For research use only

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Alternative names

Technical specifications

Figure 1

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