YILIMART - Anti-XCR1-APC, m, REAL241, 100 tests

Clone REAL241 is an antibody fragment derived from the full XCR1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.

Clone REAL241 recognizes the mouse XCR1 antigen, also known as GPR5. XCR1 is a G protein–coupled chemokine receptor for XCL1 and XCL2 also known as lymphotactin-1 and -2. XCR1 is highly expressed in CD8α

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dendritic cells. It plays a role in signal transduction by increasing the intracellular calcium ions level.

The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

GPR5, mXCR1, CCXCR1, SCM1 receptor, XC chemokine receptor, Lymphotactin receptor

Technical specifications

Antigen: XCR1
Clone: REAL241
Isotype control: REAL Control
Alternative names of antigen: GPR5, mXCR1, CCXCR1, SCM1 receptor, XC chemokine receptor, Lymphotactin receptor
Distribution of antigen: dendritic cells
Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Storage: Store protected from light at 2–8 °C. Do not freeze.
Available conjugates: APC

Figure 1

Splenocytes from C57BL/6 mice were stained with REAlease Anti-XCR1-APC (B) or with the corresponding REAL Control (A). REAlease Anti-XCR1-APC was released using the REAlease Release Reagent (C). To show epitope accessibility after REAlease Complex release, the cells were washed with the REAlease Stop Reagent and restained with REAlease Anti-XCR1-APC (D). Cells were labeled with CD8a antibodies in addition and analyzed by flow cytometry using the MACSQuant

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Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide (PI) fluorescence.

A:	B:

C:	D:

Anti-XCR1-APC, m, REAL241, 100 tests

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Technical specifications

Figure 1

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