CD159a (NKG2A)-PE, mouse, REA1161, 500 t


For research use only
货号:
130-120-371
描述:
CD159a (NKG2A)-PE, mouse 
包装:
150 µg in 1 mL  
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原产地:




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Clone REA1161 recognizes the CD159a (NKG2A) antigen, an inhibitory natural killer (NK) cell receptor. CD159a forms heterodimer with CD94 and contains a C-type lectin ectodomain. Inhibitory signal is transmitted by the heterodimer via immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and upon ligand engagement, ITIMs are phosphorylated and transmit signal through docking of various tyrosine phosphatases. CD159a/CD94 binds non-classical MHC class I protein, HLA-E. Expression of CD159a is found mainly on NK cells, NKT cells, and on subsets of CD8
+
cells.
Additional information: Clone REA1161 displays negligible binding to Fc receptors.

Alternative names

KLRC1, NKG2A