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CD182 (CXCR2)-APC, human, REA208, 30 t


For research use only
货号：
130-120-133
描述：
CD182 (CXCR2)-APC, human 
包装：
for 30 tests  
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原产地：
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Clone REA208 recognizes CD182 (CXCR2), which belongs to the class of chemokine receptors specific for CXC chemokines. Chemokine receptors are G-coupled protein receptors (GPCR) with seven-transmembrane domains and consist of an α-subunit and a βγ-complex. In humans, interleukin 8 (IL-8) is one of most potent chemokine which binds to CXCR2. Expression of CD182 is found on several cell types including leukocytes, endothelial, and epithelial cells. CD182 plays a critical role in neutrophil homeostatis, angiogenesis, and in pathological conditions such as acute lung injury, lung diseases, and asthma.
Additional information: Clone REA208 displays negligible binding to Fc receptors.

Alternative names

CXCR2, CDw128b, CMKAR2, IL8R2, IL8RA, CD128b, IL-8RB