YILIMART - CD66abce-APC-Vio770, human, TET2, 30 t

CD66 constitutes a gene family whose members belong to the family of carcinoembryonic antigens (CEA). They are involved in a wide variety of physiological processes such as embryonic development, pregnancy, bile transport, as well as pathological conditions such as cancer, bacterial or viral infection, and inflammation.

CD66a (CEACAM1), CD66b (CEACAM8), CD66c (CEACAM6), and CD66e (CEACAM5) are differentially expressed on some epithelial cells as well as on T cells, NK cell subsets, and granulocytes, especially neutrophils.

Alternative names

CEACAM1, CEACAM5, CEACAM8, CEACAM6, BGP, CD67, CEA, CGM6, NCA, NCA-160

Technical specifications

Antigen: CD66abce
Clone: TET2
Isotype: mouse IgG2bκ
Isotype control: Mouse IgG2b – isotype control antibodies
Alternative names of antigen: CEACAM1, CEACAM5, CEACAM8, CEACAM6, BGP, CD67, CEA, CGM6, NCA, NCA-160
Entrez Gene ID: 634, 1088, 4680, 1048
Molecular mass of antigen [kDa]: 30-70
Cross-reactivity:

rhesus monkey (
Macaca mulatta
)

,

cynomolgus monkey (
Macaca fascicularis
)
Distribution of antigen: epithelial cells, granulocytes, liver, macrophages, myeloid cells, NK cells, T cells
Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
Storage: Store protected from light at 2–8 °C. Do not freeze.
Available conjugates: PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin, FITC

Figure 1

White blood cells (WBCs) were stained with CD66abce antibodies and analyzed by flow cytometry using the MACSQuant

^®

Analyzer. The Tandem Signal Enhancer has been used to increase binding specificity of tandem-dye–conjugated antibodies. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4',6-diamidino-2-phenylindole (DAPI) fluorescence, as in the case of tandem conjugates.

Figure 2
View details

Figure 2

Rhesus monkey lysed blood was stained with CD66abce-PE and analyzed by flow cytometry.

Rhesus monkey lysed blood was stained with CD66abce-PE and analyzed by flow cytometry.
Figure 3
View details

Figure 3

Cynomolgus monkey lysed blood was stained with CD66abce-APC and analyzed by flow cytometry.

Cynomolgus monkey lysed blood was stained with CD66abce-APC and analyzed by flow cytometry.