CD137-Biotin, human, 4B4-1, 100 tests


For research use only
货号:
130-119-884
描述:
CD137-Biotin, human 
包装:
for 100 tests  
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This antibody recognizes the CD137 (4-1BB) antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily. CD137 is mainly expressed on activated CD4
+
and CD8
+
T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells.
As a costimulatory molecule it is involved in the activation and survival of CD4
+
or CD8
+
T cells, and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8
+
T cells, as it is not expressed on resting CD8
+
T cells and its expression is reliably induced after 24 hours of stimulation.

Alternative names

TNFRSF9, 4-1BB, CDw137, ILA