YILIMART - CD138-APC-Vio770, human, 44F9, 100 tests

Clone 44F9 recognizes the human CD138 antigen, a transmembrane heparan sulfate proteoglycan macromolecule also known as syndecan-1. The CD138 molecule interacts with extracellular matrix proteins, cell surface molecules, and other soluble proteins. It is expressed on normal and malignant human plasma cells and on basolateral surfaces of endothelial cells but not on virgin/naive B cells, memory B cells, T cells, or monocytes. Clone 44F9 recognizes similar epitope as clone B-B4.

Alternative names

SDC1, SDC, Synd1

Technical specifications

Antigen: CD138
Clone: 44F9
Isotype: mouse IgG1κ
Isotype control: Mouse IgG1 – isotype control antibodies
Alternative names of antigen: SDC1, SDC, Synd1
Entrez Gene ID: 6382
Molecular mass of antigen [kDa]: 30
Distribution of antigen: B cells, breast, endothelial cells, epithelial cells, neurons, plasma cells, smooth muscle
Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
Storage: Store protected from light at 2–8 °C. Do not freeze.
Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515, Biotin

Figure 1

A mixture of human peripheral blood mononuclear cells (PBMCs) and cells of the human myeloma cell line U266 was stained with CD138 antibodies and analyzed by flow cytometry using the MACSQuant

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Analyzer. The Tandem Signal Enhancer has been used to increase binding specificity of tandem-dye–conjugated antibodies. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4',6-diamidino-2-phenylindole (DAPI) fluorescence, as in the case of tandem conjugates.

Selected references
1. Couchman, J. R. et al. (1996) Syndecans, signaling, and cell adhesion. J. Cell. Biochem. 61: 578-584
2. Bernfield, M. et al. (1992) Biology of the syndecans: a family of transmembraneheparan sulfate proteoglycans. Annu. Rev. Cell Biol. 8: 365-393

CD138-APC-Vio770, human, 44F9, 100 tests

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Technical specifications

Figure 1

Selected references

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