YILIMART - CD16/CD32-VioBright FITC, mouse 60 tests

The CD16/32 antibody recognizes a shared epitope common to the CD16 and CD32 antigens. CD16 and CD32 are also known as FcγIII and FcγII, respectively, and bind to epitopes located in the constant region domain of IgG.

CD16 and CD32 are expressed predominantly on cells of hematopoietic lineages, including B cells, monocytes, NK cells, granulocytes, and dendritic cells. They are also found on hematopoietic progenitor cells, where they appear to play a role in T and B cell development.

Clone 93 monoclonal antibody blocks the binding of immunoglobulins to the Fc receptor.

Alternative names

FCGR2B, FCGR3, FcRII

Technical specifications

Antigen: CD16/CD32
Clone: 93
Isotype: rat IgG2aλ
Isotype control: Rat IgG2a – isotype control antibodies
Alternative names of antigen: FCGR2B, FCGR3, FcRII
Entrez Gene ID: 14131
Molecular mass of antigen [kDa]: 26,6-33,4
Distribution of antigen: B cells, basophils, dendritic cells, endothelial cells, eosinophils, granulocytes, Langerhans cells, leukocytes, lymphocytes, macrophages, monocytes, myeloid cells, neutrophils, NK cells, placenta, plasma cells, platelets
Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
Storage: Store protected from light at 2–8 °C. Do not freeze.
Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin, pure

Figure 1

Splenocytes from C57BL/6 mice were stained with CD16/CD32 antibodies or with the corresponding isotype control antibodies (left image) without FcR Blocking Reagent. Cells were then analyzed with the MACSQuant

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Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4',6-diamidino-2-phenylindole (DAPI).

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CD16/CD32-VioBright FITC, mouse 60 tests

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Alternative names

Technical specifications

Figure 1

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