ExiTron V is a non-ionic, dimeric, hexaiodine-based contrast agent of low molecular weight specifically formulated for pre-clinical computed tomography (CT).
It shows strong X-ray absorption due to its covalently bound iodine atoms.
Upon intravenous injection, ExiTron V shows low plasma protein–binding and is rapidly distributed in the extracellular space.
ExiTron V is mainly excreted unchanged via glomerular filtration (kidneys).
Applications
ExiTron V is indicated for use in CT of small animals, for example mice, to facilitate the visualization of the vasculature.
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Larsen, L. E. et al. (1995) Neural tolerability of iodixanol in mice and dogs after single and repeated intracisternal administration. Acta Radiol. Suppl. 399: 238-243
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