ExiTron nano 6000 is an alkaline earth metal-based nanoparticulate contrast agent specifically formulated for preclinical computed tomography (CT).
It shows strong X-ray absorption due to the high metal load of theparticles.
Upon intravenous injection, ExiTron nano 6000 circulates in the blood stream and is taken up by the Kupffer cells (macrophages of the liver). It accumulates particularly in the liver and spleen and provides long-term X-ray contrast.
Applications
ExiTron nano 6000 is indicated for use in CT of small animals, for example mice, to facilitate the visualization of the liver and spleen.
Examples include imaging of liver tumors and metastases.
Schematic diagram of an ExiTron nano 6000 nanoparticle.
Schematic diagram of an ExiTron nano 6000 nanoparticle.
Selected references
Boll, H. et al. (2010) High-speed single-breath-hold micro-computed tomography of thoracic and abdominal structures in mice using a simplified method for intubation. J. Comput. Assist. Tomogr. 34: 783-790
Boll, H. et al. (2011) Micro-CT based experimental liver imaging using a nanoparticulate contrast agent: a longitudinal study in mice. PLoS One 6: e25692
View details 
