YILIMART - MACS GMP CD127-FITC

MACS

^®

GMP CD127 Fluorescent Antibodies consist of a mouse monoclonal antibody against the human CD127 antigen conjugated to a fluorochrome. They are developed for flow cytometric identification and flow cytometric sorting of CD127-positive cells.

Disclaimer

MACS GMP Products are for research use and

ex vivo

cell culture processing only, and are not intended for human

in vivo

applications. For regulatory status in the USA, please contact your local representative.

Background information

Clone MB15-18C9 recognizes the CD127 antigen, which is the α-chain of the IL-7 receptor, a type I membrane glycoprotein.

The CD127 antigen can be identified on immature B cells through the early pre-B stage, on thymocytes, and on most mature T cells with transient down-regulation upon activation. On regulatory T cells CD127 is absent and its expression is inversely correlated with FoxP3 expression and suppressive function. CD127 is also used by thymic stromal derived lymphopoietin (TSLP) as part of a complex.

Applications

MACS GMP CD127 Fluorescent Antibodies are for identification of CD127 positive cells by flow cytometry as well as cell enrichment by flow cytometric sorting.

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Figure 1

A leukapheresis sample was labeled with MACS

^®

GMP CD127 antibodies conjugated to FITC or APC and MACS GMP CD4-VioBlue

^®

for gating purposes. Cells were analyzed by flow cytometry using the MACSQuant

^®

Analyzer 10. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Brochures and posters

MACS GMP Tyto Consumables flyer

MACS

GMP Fluorescent Antibodies
Scientific posters

GMP-compliant flow cytometric cell sorting of antigen-specificT cells using MACS
^®
GMP CD8-APC and MACS GMP CD137-PEFluorescent Antibodies on the MACSQuant
^®
Tyto
^®
Cell Sorter. Christiane Siewewrt
et. al. CIMT (2019)
Special protocols

MACS GMP Protocol cell sort on MACSQuant Tyto

MACS GMP Fluorescent Antibodies
Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

查看数据文件查看下载

MACS GMP CD127-FITC

For research use and ex vivo cell processing only

您浏览过的商品

Disclaimer

Background information

Applications

Quality statement

Figure 1

Brochures and posters

Scientific posters

Special protocols

Certificates

相关产品