Applications

Background information

Quality description

Biological activity

• Proliferation of human TF-1 cells
• research grade: ≥ 2×

  10

  ³

  U/mg

• Selected references

  1. Batten, M. et al. (2006) Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat. Immunol. 7(9): 929-936
  2. Devergne, O. et al. (1997) Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin. Proc. Natl. Acad. Sci. U.S.A. 94(22): 12041-12046
  3. Diveu, C. et al. (2009) IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells. J. Immunol. 182: 5748-5756
  4. Hisada, M. et al. (2004) Potent antitumor activity of interleukin-27. Cancer Res. 64(3): 1152-1156
  5. Pflanz, S. et al. (2002)
     IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4

     ⁺

     T cells.
     Immunity 16(6): 779-790
  6. Seita, J. et al. (2008) Interleukin-27 directly induces differentiation in hematopoietic stem cells. Blood 111(4): 1903-1912

• Certificates

  Please follow this

  link

  to search for Certificates of Analysis (CoA) by lot number.