MIP-3β stands for macrophage inflammatory protein 3β, also termed CCL19. Mouse MIP-3β is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.
Applications
Mouse CCL19 (MIP-3β) can be used for a variety of applications, including:
Study of lymphoid an myeloid cell migration via chemotactic assays.
Maturation of dendritic cells and induction of T cell proliferation.
Alternative names
CCL19, ELC, Exodus 3
Background information
MIP-3β belongs to the CC chemokine family and is also known as CCL19. MIP-3β is expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells.
Quality description
Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.
