YILIMART - MACS GMP CD45RA-APC

MACS

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GMP CD45RA Fluorescent Antibodies consist of a mouse monoclonal antibody against the human CD45RA antigen conjugated to a fluorochrome. They are developed for flow cytometric identification and flow cytometric sorting of CD45RA-positive cells.

Disclaimer

MACS GMP Products are for research use and

ex vivo

cell culture processing only, and are not intended for human

in vivo

applications. For regulatory status in the USA, please contact your local representative.

Background information

The CD45RA antibody (clone T6D11) recognizes the 220 kDa isoform of the leukocyte common antigen (LCA), a transmembrane tyrosine phosphatase.

The CD45RA antigen is expressed on CD4

⁺

and CD8

⁺

T cell subsets, as well as on subsets of B cells, NK cells, and monocytes.

Applications

MACS GMP CD45RA Fluorescent Antibodies are for identification of CD45RA positive cells by flow cytometry as well as cell enrichment by flow cytometric sorting.

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Figure 1

A leukapheresis sample was labeled with MACS

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GMP CD45RA-APC and CD45-FITC for gating purposes. Cells were analyzed by flow cytometry using the MACSQuant

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Analyzer 10. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence. Viable cells were further gated on CD45

⁺

cells.

Brochures and posters

MACS GMP Tyto Consumables flyer

MACS

GMP Fluorescent Antibodies
Scientific posters

GMP-compliant flow cytometric cell sorting of antigen-specificT cells using MACS
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GMP CD8-APC and MACS GMP CD137-PEFluorescent Antibodies on the MACSQuant
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Tyto
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Cell Sorter. Christiane Siewewrt
et. al. CIMT (2019)
Special protocols

MACS GMP Protocol cell sort on MACSQuant Tyto

MACS GMP Fluorescent Antibodies
Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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MACS GMP CD45RA-APC

For research use and ex vivo cell processing only

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Disclaimer

Background information

Applications

Quality statement

Figure 1

Brochures and posters

Scientific posters

Special protocols

Certificates

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