YILIMART - MACS GMP CD38-APC

MACS

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GMP CD38 Fluorescent Antibodies consist of a mouse monoclonal antibody against the human CD38 antigen conjugated to a fluorochrome. They are developed for flow cytometric identification and flow cytometric sorting of CD38-positive cells.

Alternative names

ADP-ribosyl cyclase, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Disclaimer

MACS GMP Products are for research use and

ex vivo

cell culture processing only, and are not intended for human

in vivo

applications. For regulatory status in the USA, please contact your local representative.

Background information

Clone IB6 recognizes the human CD38 antigen, a cell surface protein that exhibits receptor and enzymatic functions. This protein is highly expressed on plasma cells and expressed at lower levels on various hematopoietic and solid tissues. In the immune system CD38 plays a role in adhesion and transmigration through the endothelial layer. In addition, it can trigger the activation and proliferation of leukocytes. CD38 has cyclase as well as hydrolase activity.

Applications

MACS

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GMP CD38 Fluorescent Antibodies are for identification of CD38-positive cells by flow cytometry as well as cell enrichment by flow cytometric sorting.

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Figure 1

A mobilized leukapheresis sample was labeled with MACS

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GMP CD38-APC and MACS GMP CD34-PE for gating purposes. Cells were analyzed by flow cytometry using the MACSQuant

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Analyzer 10. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Brochures and posters

MACS GMP Tyto Consumables flyer
Scientific posters

GMP-compliant flow cytometric cell sorting of antigen-specificT cells using MACS
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GMP CD8-APC and MACS GMP CD137-PEFluorescent Antibodies on the MACSQuant
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Tyto
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Cell Sorter. Christiane Siewewrt
et. al. CIMT (2019)
Special protocols

MACS GMP Protocol cell sort on MACSQuant Tyto
Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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MACS GMP CD38-APC

For research use and ex vivo cell processing only

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Alternative names

Disclaimer

Background information

Applications

Quality statement

Figure 1

Brochures and posters

Scientific posters

Special protocols

Certificates

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