YILIMART - Human IL-31, research grade (2 μg)

Human IL-31, research grade (2 μg)

For research use only

货号：: 130-112-956
描述：: Human IL-31, research grade
包装：: 2 µg

- +

添加到购物车

您浏览过的商品

Human IL-31 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human IL-31 can be used for a variety of applications, including:

Skin disease research.
Dendritic cell research.

Background information

Human IL-31 plays a role in inflammation of the skin. It is preferentially produced by type 2 helper T cells. IL-31 signals via a receptor complex that is composed of IL-31 receptor A (IL31RA) and oncostatin M receptor subunits. These receptor subunits are expressed in activated monocytes and in unstimulated epithelial cells. Signaling also involves the JAK/STAT pathway, the PI3 kinase/AKT cascade, and the MAP kinase pathway.

Quality description

Research-grade

cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Biological activity

STAT3 activation in human U87 cells.

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

查看数据文件查看下载