IP-10 stands for interferon-inducible protein 10, also termed CXCL10. Mouse IP-10 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.
Applications
Mouse IP-10 can be used for a variety of applications including:
In vitro inhibition of cell proliferation.
Chemotactic studies.
Alternative names
CXCL10
Background information
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Tʜ1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells.
Quality description
Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.
