Interleukin 1 alpha (IL-1α) is a cytokine that participates in the regulation of immune responses, inflammatory reactions, and hematopoiesis. IL-1α is produced mainly by activated macrophages as well as neutrophils, epithelial cells, and endothelial cells. It is involved in lymphocyte proliferation, inducing IL-2 release, B cell maturation and proliferation, and immunoglobulin secretion. In addition, it also plays a role in fibroblasts proliferation.
