YILIMART - SuperMACS II Separator

Developed for large-scale cell separations, the SuperMACS™ II Separator can be used in combination with any MACS

^®

Column for manual cell separation.

The SuperMACS II Separator is provided with three column adapters to insert MACS Columns into the magnetic field.

Background information

The SuperMACS II Separators contains a powerful permanent magnet that induces a high-gradient magnetic field within MACS Columns – a field strong enough to retain cells labeled with even small amounts of MACS MicroBeads.

Applications

In addition to many applications using MACS MicroBeads, the SuperMACS™ II Separator in combination with LD Columns

¹

have been used for the enrichment of

Plasmodium falciparum–

infected erythrocytes without magnetic labeling

²

. The malaria parasites digest red blood cell hemoglobin, resulting in the formation of hemozoin. The paramagnetic properties of hemozoin allow magnetic isolation of red blood cells without the need for further labeling.

Figure 1
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Figure 1

The SuperMACS™ II Separator, shown with a D Column and the MACS® Acrylic Tube Rack.

The SuperMACS™ II Separator, shown with a D Column and the MACS® Acrylic Tube Rack.
Figure 2
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Figure 2

An LS Column placed in the magnetic field of a SuperMACS™ II Separator using an Adapter for MS, LS, and LD Columns.

An LS Column placed in the magnetic field of a SuperMACS™ II Separator using an Adapter for MS, LS, and LD Columns.

Selected references
1. Uhlemann, A. C. et al. (2000) MACS&more 4(2): 7-8
2. Staalsoe, T. et al. (1999)
  
  Detection of antibodies to variant antigens on
  Plasmodium falciparum
  -infected erythrocytes by flow cytometry.
  
  Cytometry 35(4): 329-336

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SuperMACS II Separator

For research use only

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Background information

Applications

Figure 1

Figure 1

Figure 2

Figure 2

Selected references

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